CV

  • Honorary Associate Professor and Consultant Surgeon
  • Consultant Surgeon | Peripheral Nerve Injury Unit | Royal Nation Orthopaedic Hospital, Stanmore HA7 4LP
  • Hon Associate Professor | Insitute of Orthopaedics and Musculoskeletal Science | UCL | HA7 4LP
  • Honorary Surgeon | Great Ormond St Hospital, London | & Defence Military Rehab Centre | Headley Court, Surrey
  • Head of Undergraduate Education, Division of Surgery | Honorary Senior Lecture Institute of Musculoskeletal Science UCL
  • GMC 6031675 | MDU 393730G
  • NHS contact details : juliettehoughton@nhs.net | 0208 9095447 |
  • Private contact details:  NerveInjuryLondon@gmail.com |  07545 684 524

Profile

Tom is a Fellowship trained  Clinical Academic Peripheral Neurosurgeon with a Paediatric Orthopaedic background. His NHS practice is 50:50 paediatric and adults and encompasses all aspects of nerve injury treatment from primary intervention to later reconstruction in the neonate, child, adolescent and adult.

Tom’s interests in his paediatric pactice are Obstetric Brachial Palsy (Erb’s palsy) traumatic nerve injury, nerve injury and development in the growing shoulder and adult brachial plexus injury.

Tom interests in his adult practice are thoracic outlet syndrome (TOS), brachial plexus injury,  targeted muscle reinnervation (TMR), brachial plexus tumour, nerve compression syndromes, nerve transfer, nerve graft, tendon transfer, amputation, schwannoma, cubital tunnel and carpal tunnel primary and revision surgery.

The RNOH PNI (NHS) unit offers

  • spinal root re-implantation
  • targetted muscle renervation
  • nerve stimulator pain modulation service
  • obstetric shoulder specialist clinic
  • quantitative sensory testing
  • one stop nerve conduction and EMG clinics
  • and a fully integrated multidisciplinary team approach

Tom has research collaborations across UCL within the Centre for Nerve Engineering  (CNE)  and Centre for Medical imaging and computing  (CMIC) and is currently engaged in exploratory science projects towards direceting and augmenting nerve regeneration, MRI neurography and cell therapies . His clinical projects centre around obstetric palsy assessment and treatment, co-contraction, improvements and quantification of nerve recovery and muscle reinnervation and medical education.

Current Appointments

  • Consultant Surgeon, Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, Stanmore, UK (2013-)
  • Honorary Associate Professor, Institute of Orthopaedics and Musculoskeletal Science, University College London, UK (2019-)
  • Clinical lead for Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital (2018-)
  • Director of research Peripheral Nerve Injury Research Unit (PNIRU) (2017-)
  • Clinical lead for peripheral nerves, Centre for Nerve Engineering (CNE) UCL (2017-)
  • Honorary Senior Lecturer, Institute of Orthopaedics and Musculoskeletal Science, University College London, UK (2013-2019)
  • Honorary Consultant Surgeon, Great Ormond Street Hospital, London (2012-)
  • Honorary Consultant Surgeon, Evelina Children’s Hospital, London (2015-)
  • Consultant Surgeon, Princess Grace Hospital (HCA), (2017-)
  • Consultant Surgeon, The Portland Women and Childrens’ Hospital (HCA) (2016-)
  • Consultant Surgeon, King Edward VIIth Hosptial (2020-)

Education & Qualifications

  • Manchester Grammar school, Manchester, 10GCSEs 3 A-levels 2 S-levels
  • Magdalene College, Cambridge, History of Art MA(Cantab) and MB exemptions
  • University College Hospital, London (Royal Free Campus) MBBS
  • Royal College of Surgeon of Edinburgh, MRCS(Ed)
  • Intercollegiate board of Surgeons, FRCS(Tr&Orth) (2011)
  • Paediatric orthopaedic Fellow, Westmead children’s hospital (2011-2012)
  • Post-graduate fellow, PNI unit RNOH (2010 and 2013)
  • Fellow Higher Eductation Academy (FHEA) (2015-)
  • MD (res), UCL 2018

Clinical Skills

Tom has one of the largest obstetric palsy practices in the United Kingdom providing huge experience in this very focused field. He sees over 150 new patients with OBPP per year and has inherited the long term follow up of over 2500 patients whom he sees regularly.

As part of providing a national referral service for Adult and paediatric brachial plexus and peripheral nerve injury Tom has a large experience of traumatic supra- and infra-clavicular plexal injury repair and reconstruction. Microsurgical graft and transfer and secondary reconstruction cases are managed through a rapid access clinic with structured follow up and rehabilitation programmes to support these patients. Treatment of co-contraction is another area of clinical expertise in both adults and children where Tom has a focused interest.

Within the diagnosis treatment and reconstuction of complex nerve injury all over the body (except the face) Tom deploys all modern methods of nerve surgery:

nerve transfer, nerve grafting (both autograft & allograft), neruolysis, neuroma relocation, targetted muscle reinnervation (TMR).

Research

Tom was awarded MD(res) by UCL in assessing motor outcomes following re-innervation of skeletal muscle following a two year period of study.

Tom has also designed a large programme of tissue research; The first project of this focuses on characterising the in vivo phenotypic changes of denervation to human Schwann cells. This study has completed and is under peer-review having been presented internationally.

A RCT studying a human model of augmentation of nerve repair is currently underdevelopment pending information from a currently running pilot to allow power analysis prior to funding being pursued in conjunction with the UCL Clinical trials unit.

Tom has secured access to the National trauma audit and research network database (TARN) to review the demographics for the UK’s supraclavicular plexus injury burden. This work is under peer review currently; a secondary project to review outcomes from this cohort has also been submitted.

Tom has a strong interest in the clinical assessment of Erb’s palsy; Two studies on self-image and the impact of linguistic and socioeconomic poverty on the incidence of OBPP in England are now submitted and two further projects on gait and balance in Erbs Palsy using wireless motion capture in the clinical environment are due to commence in autumn 2018.

Collaboration

The UCL Centre for Nerve Engineering (CNE) was established in 2016 with Professor James Phillips and Professor Rebecca Shipley formalising relationships between medical physics, imaging, tissue engineering, mathematical modelling and synthetic pharmacology in peripheral nerve regeneration. Tom is clinical lead for peripheral nerves system. The Peripheral Nerve Injury Research Unit (PNIRU) is the embodiment of this clinical research and coordinates all the clinical projects run through the Royal National Orthopaedic Hospital. In the PNRIU team, Tom contributes to a team from a wide background of clinical research and clinical expertise. Tom also collaborates with the Centre for Medical Image Computing (CMIC), ASpire Create engineering and rehabilitation group, University of Texas At Austin.

Medicolegal Career

Starting in 2013, and having now been instructed in excess of 500 cases encompassing personal injury and medical negligence. Tom sees 2 new medicolegal cases for opinion per week with a ratio of 70:30 between claimant and defence instruction.

He accepts instructions via a paper-free practice and has a turn around of 6-8 weeks from receiving instruction to completed reports (with video and static image evidence).

Tom has a wealth of experience in court appearances. Having appeared (both as a witness to fact and an expert witness) in personal injury, medical negligence, criminal and family courts. In all court appearances the side calling Mr Quick as an expert were successful. Senior Counsel Liam Reidy in Dublin comment that in under cross examination Tom was “brilliant and remained composed”.

A large percentage of Tom’s reports concern both the condition and prognosis and the likely causation of cases of Obstetric (Erb’s) Palsy. In commenting on causation Tom restricts his comments to the pathophysiology of nerve injury not straying into the area of the obstetric expert but offering supportive evidence to that of the midwife or obstetrician.

Tom has attended training at Irwin Mitchell’s ‘Becoming a Medico-Legal Expert’ Spring Series 2014 and attended the Expert Witness Institute Conference 2015. Tom was elected as a member of the Expert Witness Institute in 2015. Tom has provided educational talks to lawyers and medical experts on issues around nerve injury (some of which are available to view on his website). Tom is a member of the organising committee of the Annual Cambridge (Peterhouse) Medicolegal conference which hopes to return in 2021 after a COVID recess in 2020.

Publications

Publications – https://orcid.org/0000-0002-5342-1509

Wilcox M, Laranjeira S, Brown H, Quick T. How to assess the recovery of muscular function following nerve injury: A view from surgeons and patients. J Plast Reconstr Aesthet Surg. 2020 Dec 11:S1748-6815(20)30649-5.

Wilcox M, Gregory H, Powell R, Quick TJ, Phillips JB. Strategies for Peripheral Nerve Repair. Curr Tissue Microenviron Rep. 2020;1(2):49-59

Dean BJF; Corona Hands Collaborative. Mortality and pulmonary complications in patients undergoing upper extremity surgery at the peak of the SARS-CoV-2 pandemic in the UK: a national cohort study. BMJ Qual Saf. 2020 Oct 9:bmjqs-2020-012156.

Brown H, Quick T J, The characterisation of pain reported by children with brachial plexus birth injury. Association of paediatric charted physiotherapists Journal 11. 3 (2020) 22-27

Wilcox Matthew B, Jessen Kristjan R, Quick Tom J, Phillips James B The molecular profile of nerve repair: humans mirror rodents Neural Regeneration Research 2021 16 7(1440-1441)

Simpson AI, Vaghela KR, Brown H, Adams K, Sinisi M, Fox M, Quick T J Reducing the Risk and Impact of Brachial Plexus Injury Sustained From Prone Positioning—A Clinical Commentary. Journal of Intensive Care Medicine. 2020;35(12):1576-1582.

Wilcox, M.B., Laranjeira, S.G., Eriksson, T.M., Jesson KR, MIrsky R, Quick TJ, Phillips JB Characterising cellular and molecular features of human peripheral nerve degeneration. Acta Neuropathol Commun 8, 51 (2020)

Barrett P, Quick TJ, Mudera V, Player DJ. Generating intrafusal skeletal muscle fibres in vitro: Current state of the art and future challenges. Journal of Tissue Engineering. January 2020.

Rayner MLD, Brown H, Wilcox M, Phillips JB , Quick TJ. Quantifying regeneration in patients following peripheral nerve injury. Journal of Plastic, Reconstructive & Aesthetic Surgery 2019. in press.

Merrison H, Mangtani A, Quick T, The shifting demographics of birth-related brachial plexus injury: The impact of socio-economic status and ethnic groups, Journal of Plastic, Reconstructive & Aesthetic Surgery, 2020,

Brown, H, Bassett, P, Quick, TJ. Inter- and intra-rater reliability and clinical utility of the Brachial Plexus Outcome Measure: A pilot study. Hand Therapy, 24(4), 123–129. https://doi.org/10.1177/1758998319861655

Quick TJ, Brown H. Evaluation of functional outcomes after brachial plexus injury. J Hand Surg Eur Vol. 2019 Oct 9:1753193419879645.

Bartlett RD, Momin SMB, Azam S, Rotimi O, Quick TJ Development of a “Surgical Shadowing Scheme” to improve undergraduate experiences of surgery. Advances in Medical Education and Practice, August 2019

Wilcox M, Brown H, Johnson K, Sinisi M, Quick TJ. An assessment of fatigability following nerve transfer to reinnervate elbow flexor muscles. Bone Joint J. 2019 Jul;101-B(7):867-871.

Wilcox M, Quick TJ, Phillips JB. The Effects of Surgical Antiseptics and Time Delays on RNA Isolated From Human and Rodent Peripheral Nerves. Front Cell Neurosci. 2019 May 22;13:189.

Brown H, Johnson K, Gilbert A, Quick TJ. The lived experience of motor recovery of elbow flexion following Oberlin nerve transfer: A qualitative analysis Hand Therapy 2018 Volume: 23 issue: 4, page(s): 130-138

Donatien P, Anand U, Yiangou Y,, Sinisi, M., Fox, M., MacQuillan, A., Quick, T., Korchev, Y. E.,Anand, P. Granulocyte-macrophage colony-stimulating factor receptor expression in clinical pain disorder tissues and role in neuronal sensitization. Pain Rep. 2018;3(5):e676. Published 2018 Sep 17.

Anand U, Yiangou Y, Akbar A, Quick T, MacQuillan A, Fox M, Sinisi M, Korchev YE, Jones B, Bloom SR, Anand P. Glucagon-like peptide 1 receptor (GLP-1R) expression by nerve fibres in inflammatory bowel disease and functional effects in cultured neurons. PLoS One. 2018 May 29;13(5):e0198024.eCollection 2018.

Singh AK, Rudge W, Quick T. An important lesson in assessing neurovascular involvement in proximal humeral fractures: the presence of neuropathic pain in a dysvascular limb. J Shoulder Elbow Surg. 2018 Jan;27(1):e20-e24.

Kakkar LS, Bennett OF, Siow B, Richardson S, Ianuş A, Quick T, Atkinson D, Phillips JB, Drobnjak I. Low frequency oscillating gradient spin-echo sequences improve sensitivity to axon diameter: An experimental study in viable nerve tissue. Neuroimage. 2017 Aug 1.

Anand P, Yiangou Y, Anand U, Mukerji G, Sinisi M, Fox M, McQuillan A, Quick T, Korchev YE, Hein P. Nociceptin/orphanin FQ receptor expression in clinical pain disorders and functional effects in cultured neurons. Pain. 2016 Sep;157(9):1960-9.

T J Quick, A Singh, M Fox, M Sinisi, A MacQuillan. A quantitative assessment of the functional recovery through nerve transfer reconstruction of elbow flexion in patient with a brachial plexus injury. aBone Joint J 2016;98-B:1517–20.

Abdul-Jabar HB, Bhamra J, Quick TJ, Fox M. Iatrogenic posterior tibial nerve division during a combined anterior ankle arthroscopy with an additional posterolateral portal. J Surg Case Rep. 2016 May 19;2016(5).

Kwok IH, Silk ZM, Quick TJ, Sinisi M, MacQuillan A, Fox M. Nerve injuries associated with supracondylar fractures of the humerus in children: our experience in a specialist peripheral nerve injury unit. Bone Joint J. 2016 Jun;98-B(6):851-6.

Anand, U., Yiangou, Y., Sinisi, M., Fox, M., MacQuillan, A, Quick, T, et al. (2015). Mechanisms underlying clinical efficacy of Angiotensin II type 2 receptor (AT2R) antagonist EMA401 in neuropathic pain: clinical tissue and in vitro studies. Molecular Pain, 1–12.

Anand U, Sinisi M, Fox M, Macquillan A, Quick T, Korchex Y, Bountra C, McCarty Tm Annand P.Mycolactone-mediated neurite degeneration and functional effects in cultured human and rat DRG neurons: Mechanisms underlying hypoalgesia in Buruli ulcer. Molecular Pain. January 2016.

J Sowno, T J Quick, E Carpenter, J DeLima, P Gibbons, D Little. Near-infrared spectroscopy for detection of vascular compromise in paediatric supracondylar fractures. Journal of Physiologic Measurement Feb 2014 35(3):471.

T J Quick, A MacQuillan, M Sinisi, M Fox, R Birch. The examination and management of nerve injury in supracondylar fractures of the humerus. JPO. Part B / 07/2013; 22(4):397-8.

T Quick, Graf N, Smith N. Case report of an ulcerated infantile digital fibromatosis in an older child. The lump to spot in the child’s hand (a spot not to lump in with the others).J Hand Surg Eur Vol. 2014 Oct;39(8):888-9.

M A Tonkin, S K Tolerton, T J Quick, I Harvey, R D Lawson, N C Smith, K C Oberg. Classification of Congenital Anomalies of the Hand and Upper Limb: Development and Assessment of a New System. J Hand Surg 05/2013;2013.03.019

T J Quick, P Gibbons, N Smith. An olecranon chondral flap and osteochondral coronoid fracture in a spontaneously reduced elbow dislocation in a child. J Pediatr Orthop B. 2013 Sep;22(5):481-5.

T Quick, D M Williamson. A case of non ambulant slipped upper femoral epiphysis. J Paediatr Orthop B. 2011 July;20(4):270-272

R Amirfeyz, D Clark, T Quick, N Blewitt. Newcastle approach to the elbow, a cadaveric study. Arch Ortho Trauma Surg 2011 June;131(6):747-751

R Bethune, G Scally, R Griggs, T Quick. True grit. Journal of Public Health 2010; doi: 10.1093/pubmed/fdq033

T J Quick, D M Eastwood. Paediatric fractures and dislocations of the hip and pelvis. Clin Orthop and Related Research 2005;432:87-96

R Dilawaiz, R Nadeem, T J Quick, D M Eastwood. Focal dome osteotomy for the correction of tibial deformity in children. J Paediatr Orthop B. 2005 Sep;14(5):340-6.

T J Quick Emergency Medicine: Concepts and Clinical Practice Rosen 5th &Emergency: Diagnosis and Management Book reviews: Injury 2003 July;34(7):558

T J Quick A Surgeon’s Guide to Writing and Publishing: Schein & Farndon Book review: Injury, 2000 July;34(7):557

 

 

Book Chapters

  • Wilcox M, Brown H, Quick TJ. Clinical Outcome Measures Following Peripheral Nerve Repair Current Tissue Microenvironment Reports, Springer, New York in press.
  • Wilcox M, Quick TJ ‘Strategies for peripheral nerve repair’ in Current Tissue Microenvironment Reports, Springer, New York in press.
  • Key S, Skinner J, Quick TJ “ Total hip arthroplasty’ in “Peripheral nerve issues after orthopaedic Surgery: A Multidisciplinary approach to prevention evaluation and treatment” Springer, New York in press.
  • Dhir, R, Suggand K, T Quick. ‘Peripheral Nerve Injury’ Chapter in ABC of Orthopaedics and Trauma Eds. Gupte C M, Sugand K. 2018 John Wiley & Sons Ltd .
  • T J Quick, R Birch. ‘Nerve repair’ chapter in Green’s Hand surgery 7th Ed. Editor Scott Wolfe- Elsevier(Amsterdam) May 2016
  • T J Quick, M Fox. ‘Traumatic nerve injury chapter in Stanmore Trauma Guide Ed. S Dawson-Bowling CRC Press Publication Date: 2nd Dec 2014 | ISBN-10: 1444148826 | ISBN-13: 978-1444148824

Guidelines

National Policy & Guidelines

NICE Processed nerve allografts to repair peripheral nerve discontinuities Interventional procedures guidance [IPG597] Published date: 22 November 2017 https://www.nice.org.uk/guidance/ipg597

Intensive care society (ICS) and British Orthopaedic Society (BOA) joint guideline on “prevention, diagnosis and mangement of Plexopathy during prone positioning. 2020

Regional Anaesthesia UK (RA-UK) and British Orthopaedic Society (BOA) Algorithm for management of nerve injury associated with regional anaesthesia (unpublished)

Insight

Medical Education Videos

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Patient Information Videos

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Medicolegal Videos

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